DARA JAMIESON, MD: The first way which we may think of as being the simplest, but for some patients is truly the hardest, is lifestyle adjustment. Basically decreasing those risk factors, making sure that your physician is keeping your blood pressure under control, making sure your sugar — your glucoses are under control if you have diabetes, making sure your cholesterol is normal. Eating a good diet. If you smoke, stop. Exercise. Get your weight down.
Once you've dealt with risk factors, then there are antiplatelet medications. In some cases, there are anticoagulant medications and, in some cases, surgery that can help decrease your risk as well.
PAUL J. MONIZ: This wave of new medications is certainly increasing the likelihood that people can survive and maintain somewhat of their lifestyle. How effective are they generally?
RALPH L. SACCO, MD: What's great now is we have a lot of medicines to choose from. We think of stroke as many different types of stroke. The first thing we do is try to figure out what caused it. Then try to intervene to reduce the chance of another one occurring. If the stroke was caused by large artery blockage, then surgery is the most effective thing we can do. If the stroke was caused by the heart, then blood thinners are needed to prevent clots from forming to prevent another clot from breaking off and blocking an artery.
If it's one of the other types of stroke, some small arteries or other types, then we have a choice of antiplatelet agents. These are certain kinds of drugs that help prevent certain particles of the blood from sticking together. Something as simple as aspirin, Plavix, clopidogrel, ticlopidine or Aggrenox, the latest one to be approved to really help reduce the risk of a recurrent stroke.