M. Michael Wolfe, MD is Chief of the Section of Gastroenterology at Boston Medical Center and Boston University School of Medicine, where he is also Professor of Medicine and Research Professor of Physiology.
A native of Akron, Ohio, Dr. Wolfe received his undergraduate and medical training at Ohio State niversity. Following his graduation from medical school, he completed a residency in internal medicine at the Medical College of Pennsylvania, where he served as Chief Medical Resident. In 1979, Dr. Wolfe began his research and clinical fellowships in gastroenterology at the University of Florida, where he gained considerable expertise in the regulation of gastric acid secretion and peptic ulcer disease, as well as in the field of gastrointestinal regulatory peptides. In 1985, Dr. Wolfe relocated to Harvard Medical School, where he continued his investigative career and became one of the pioneers in studies that examined the transcriptional regulation of these peptides. His current research interests include the transcriptional regulation and physiological and pathological significance of glucose-dependent insulinotropic polypeptide. He has also initiated investigation aimed at determining the molecular mechanisms and intracellular pathways involved in mediating the trophic effects of gastrin on colorectal cancer and other malignancies of the gastrointestinal tract. His clinical investigation includes the management of acid-related disorders and novel methods for the treatment and prevention of obesity.
Dr. Wolfe has also achieved significant recognition for his continued interest in acid-related disorders and specifically GERD and NSAID-associated gastroduodenal ulcers and in the diagnosis and management of gastrinoma and other neuroendocrine tumors. He is a Fellow of the American College of Physicians and American College of Gastroenterology and was formerly Chair of the Constitution and Bylaws Committee, a member of the Research Committee, and Chair of the GERD Awareness Program (GAP) of the American Gastroenterological Association.
In addition to his numerous and significant contributions to the gastroenterological literature, he serves on the editorial boards of Digestive Diseases and Sciences and Alimentary Pharmacology and Therapeutics. Dr. Wolfe has served as editor of several clinical medicine textbooks, including his role as Editor-in-Chief of Therapy of Digestive Disorders and co-author of Heartburn: Extinguishing the Fire Inside.In all, he has authored or co-authored approximately 200 original scientific manuscripts, chapters, reviews, and abstracts. He is a member of the SSS 03 Study Section of the National Institutes of Health and is Chair of the Advisory Board for Gastrointestinal Drugs at the U.S. Food and Drug Administration.